3-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

Base Information

• Chemical Name: 3-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE
• CAS No.: 52571-71-8
• Molecular Formula: C₁₂H₁₅NO₈
• Molecular Weight: 301.253
• Hs Code.: 2932999099
• Mol file: 52571-71-8.mol

Synonyms:3-Nitrophenyla-D-galactopyranoside;m-Nitrophenyl a-D-galactopyranoside;m-Nitrophenyl-a-D-galactoside;

Chemical Property of 3-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

Chemical Property:

• Melting Point: 165 - 168 °C
• Boiling Point: 573.5 °C at 760 mmHg
• Flash Point: 300.6 °C
• PSA: 145.20000
• Density: 1.599±0.06 g/cm3 (20oC 760 Torr)
• LogP: -0.70330
• Storage Temp.: −20°C

Purity/Quality:

97% ^*data from raw suppliers

3-Nitrophenyl a-D-galactopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

There total 4 articles about 3-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

Tetra-O-acetyl-m-nitrophenyl-α-D-galactopyranosid (52571-64-9) → meta-nitrophenyl-α-D-galactopyranoside (3150-25-2,20838-44-2,28541-80-2,56140-66-0,72200-66-9,52571-71-8)

Guidance literature:

With sodium hydroxide; In methanol;

DOI:10.1021/acs.bioconjchem.8b00902

Reference yield:

D-galactose pentaacetate (25878-60-8) → meta-nitrophenyl-α-D-galactopyranoside (3150-25-2,20838-44-2,28541-80-2,56140-66-0,72200-66-9,52571-71-8)

Guidance literature:

Multi-step reaction with 3 steps

1: benzylamine / N,N-dimethyl-formamide / 20 °C

2: trifluorormethanesulfonic acid / -35 - 20 °C

3: sodium hydroxide / methanol

With trifluorormethanesulfonic acid; benzylamine; sodium hydroxide; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/acs.bioconjchem.8b00902

Reference yield:

2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate (74808-10-9,86520-63-0,87119-53-7,92052-29-4,121238-27-5,142831-80-9,127061-80-7) → meta-nitrophenyl-α-D-galactopyranoside (3150-25-2,20838-44-2,28541-80-2,56140-66-0,72200-66-9,52571-71-8)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluorormethanesulfonic acid / -35 - 20 °C

2: sodium hydroxide / methanol

With trifluorormethanesulfonic acid; sodium hydroxide; In methanol;

DOI:10.1021/acs.bioconjchem.8b00902

upstream raw materials:

D-galactose pentaacetate

2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate

Tetra-O-acetyl-m-nitrophenyl-α-D-galactopyranosid