Technology Process of (1SR,2RS,4RS,5SR)-4,5-bis(tert-butyldiphenylsilyloxy)cyclohexene oxide
There total 3 articles about (1SR,2RS,4RS,5SR)-4,5-bis(tert-butyldiphenylsilyloxy)cyclohexene oxide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
for 20h;
Ambient temperature;
DOI:10.1016/S0040-4039(98)02319-3
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: KIO3; I2; AcOH / 4 h / 60 °C
1.2: potassium acetate / acetic acid / 4 h / Heating
1.3: 74 percent / Amberlite IRA(OH); methanol / tetrahydrofuran / 16 h / 20 °C
2.1: 94 percent / imidazole / CH2Cl2 / 20 h / 20 °C
3.1: 92 percent / m-CPBA; NaHCO3 / CH2Cl2 / 20 h / 20 °C
With
1H-imidazole; potassium iodate; iodine; sodium hydrogencarbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1016/S0040-4020(02)00370-8
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 94 percent / imidazole / CH2Cl2 / 20 h / 20 °C
2: 92 percent / m-CPBA; NaHCO3 / CH2Cl2 / 20 h / 20 °C
With
1H-imidazole; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1016/S0040-4020(02)00370-8
