H-LEU-ALA-NH2 HCL

Base Information

• Chemical Name: H-LEU-ALA-NH2 HCL
• CAS No.: 87831-94-5
• Molecular Formula: C9H19 N3 O2 . Cl H
• Molecular Weight: 237.73
• Mol file: 87831-94-5.mol

Synonyms:H-LEU-ALA-NH2 HCL;L-LEUCYL-L-ALANINE AMIDE HYDROCHLORIDE

Chemical Property of H-LEU-ALA-NH2 HCL

Chemical Property:

• PSA: 98.21000
• LogP: 1.94330
• Storage Temp.: -15°C

Purity/Quality:

HPLC>98% ^*data from raw suppliers

L-LEUCYL-L-ALANINE AMIDE HYDROCHLORIDE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-LEU-ALA-NH2 HCL

There total 2 articles about H-LEU-ALA-NH2 HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-L-Leu-L-Ala-NH2 (94236-57-4) → H-Leu-Ala-NH2*HCl (87831-94-5)

Guidance literature:

With hydrogenchloride; In acetic acid;

DOI:10.1007/BF00798442

Reference yield:

(N-(tert-butoxycarbonyl)-L-leucinyl)-L-alanine methyl ester (65443-42-7,65519-50-8,129585-28-0,43189-51-1) → H-Leu-Ala-NH2*HCl (87831-94-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₃ / methanol

2: HCl / acetic acid

With hydrogenchloride; ammonia; In methanol; acetic acid;

DOI:10.1007/BF00798442

Reference yield: 84.0%

(S)-2-((S)-2-Benzyloxycarbonylamino-propionylamino)-3-phenyl-propionic acid methyl ester (3235-14-1) + H-Leu-Ala-NH2*HCl (87831-94-5) → Z-Ala-Phe-Leu-Ala-NH2 (87831-92-3)

Guidance literature:

With sodium hydroxide; sodium hydrogencarbonate; sodium carbonate; α-chymotrypsin; In tetrachloromethane; for 0.5h; Ambient temperature;

upstream raw materials:

Boc-L-Leu-L-Ala-NH₂

(N-(tert-butoxycarbonyl)-L-leucinyl)-L-alanine methyl ester

Downstream raw materials:

Z-Ala-Phe-Leu-Ala-NH₂

Nα-benzoyl-L-arginine

Refernces