1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene]

Base Information

Chemical Name:1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene]
CAS No.:158664-26-7
Molecular Formula:C₁₇H₁₈Br₂O₂
Molecular Weight:414.137
Hs Code.:
DSSTox Substance ID:DTXSID301223624
Nikkaji Number:J1.403.015H

Synonyms:DTXSID301223624;1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene];2,2'-(1,3-Propanediyl)bis(1-methoxy-4-bromobenzene);158664-26-7

Suppliers and Price of 1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene]

Chemical Property:

XLogP3:6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:413.96531
Heavy Atom Count:21
Complexity:273

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Br)CCCC2=C(C=CC(=C2)Br)OC

Technology Process of 1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene]

There total 3 articles about 1,1'-(1,3-Propanediyl)bis[5-bromo-2-methoxybenzene] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

: 124778-33-2
1,1'-(1,3-propanediyl)bis[2-methoxybenzene]

: 158664-26-7
1,1'-(1,3-propanediyl)bis(5-bromo-2-methoxybenzene)

Guidance literature:: With bromine; In chloroform; for 2h;
DOI:10.1021/jo0003044

Reference yield:

: 578-57-4
2-bromoanisole

: 158664-26-7
1,1'-(1,3-propanediyl)bis(5-bromo-2-methoxybenzene)

Guidance literature:: Multi-step reaction with 2 steps

1.1: Mg / tetrahydrofuran / 20 h / Heating

1.2: 96 percent / LiBr; CuBr*SMe₂; PhSLi / tetrahydrofuran; hexamethylphosphoric acid triamide / 22 h / Heating

2.1: 99.9 percent / Br₂ / CHCl₃ / 2 h

With bromine; magnesium; In tetrahydrofuran; chloroform; 1.1: Metallation / 1.2: Arylation / 2.1: Bromination;
DOI:10.1021/jo0003044

Reference yield:

: 578-57-4
2-bromoanisole

: 158664-26-7
1,1'-(1,3-propanediyl)bis(5-bromo-2-methoxybenzene)

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Mg; 2.) CuBr-SMe₂, LiBr, LiSPh / 1.) THF; 2.) THF, 25 deg C, 8 h

2: 75 percent / HgCl₂, TMED, Br₂ / tetrahydrofuran; diethyl ether / 25 °C

With N,N,N,N,-tetramethylethylenediamine; bromine; lithium thiophenoxide; magnesium; mercury dichloride; lithium bromide; In tetrahydrofuran; diethyl ether;
DOI:10.1016/S0040-4039(00)77060-2