1-BROMO-3,5-DIIODOBENZENE

Base Information

• Chemical Name: 1-BROMO-3,5-DIIODOBENZENE
• CAS No.: 149428-64-8
• Molecular Formula: C6H3 Br I2
• Molecular Weight: 408.803
• Hs Code.: 2903998090
• Mol file: 149428-64-8.mol

Synonyms:1-Bromo-3,5-diiodobenzene;3,5-Diiodobromobenzene

Chemical Property of 1-BROMO-3,5-DIIODOBENZENE

Chemical Property:

• Melting Point: 140℃
• Boiling Point: 341.0±32.0 °C(Predicted)
• PSA: 0.00000
• Density: 2.729
• LogP: 3.65830
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-3,5-diiodobenzene 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-BROMO-3,5-DIIODOBENZENE

There total 8 articles about 1-BROMO-3,5-DIIODOBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-bromo-2,6-diiodoaniline (89280-77-3) → 1-bromo-3,5-diiodobenzene (149428-64-8)

Guidance literature:

With copper(ll) sulfate pentahydrate; sulfuric acid; sodium nitrite; In ethanol; for 1.5h; Reflux;

DOI:10.1021/acs.inorgchem.1c01310

Reference yield: 74.0%

1,3,5-trisbromobenzene (626-39-1) → 1-bromo-3,5-diiodobenzene (149428-64-8)

Guidance literature:

1,3,5-trisbromobenzene; With tert.-butyl lithium; In diethyl ether; pentane; at -75 - -45 ℃;

With iodine; In diethyl ether; pentane; at -50 - -45 ℃; for 1.16667h; Further stages.;

DOI:10.1021/ja801646b

Reference yield: 68.0%

5-bromo-1,2,3-triiodobenzene → 1-bromo-3,5-diiodobenzene (149428-64-8)

Guidance literature:

5-bromo-1,2,3-triiodobenzene; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 1h;

With ethanol; In tetrahydrofuran; for 24h; regioselective reaction;

DOI:10.1071/CH13324

upstream raw materials:

1,3,5-trisbromobenzene

3,5-Bis-trimethylsilyl-bromobenzene

4-bromo-2,6-diiodoaniline

4-bromo-aniline

Downstream raw materials:

1-bromo-3,5-bis-[3-[4-(trimethylsilyl)phenyl]propyl]benzene

2-{3,5-bis[3-(4-trimethylsilylphenyl)propyl]phenyl}-4,4,5,5-tetramethyl[1,3,2]dioxaborane

C₆₄H₆₉BrO₂S₈

C₁₃H₈O