2'-DEOXYGUANOSINE

Base Information

• Chemical Name: 2'-DEOXYGUANOSINE
• CAS No.: 312693-72-4
• Molecular Formula: C10H13 N5 O4 . H2 O
• Molecular Weight: 285.2566
• Hs Code.: 2934999090
• Mol file: 312693-72-4.mol

Synonyms:

Chemical Property of 2'-DEOXYGUANOSINE

Chemical Property:

• Melting Point: 300oC
• Boiling Point: 801.4oC at 760 mmHg
• PKA: pK1:2.5(+1) (25°C,μ=0.1)
• Flash Point: 438.5oC
• PSA: 139.28000
• LogP: -1.07630
• Storage Temp.: Refrigerator
• Solubility.: NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow t

Purity/Quality:

99%, ^*data from raw suppliers

2′-Deoxyguanosine monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,T
• Hazard Codes: Xn,T
• Statements: 22-25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Description: 2''-Deoxyguanosine is a purine nucleoside with diverse biological activities. It inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 μM, respectively). 2''-Deoxyguanosine inhibits the growth of MOLT-4 T cells and MGL-8 B cells by 99.8 and 68.3%, respectively, when used at a concentration of 50 μM. It increases the number of binucleated cells, a marker of inhibited cytokinesis, in A. sativum meristems. 2''-Deoxyguanosine (>1 μM) also induces relaxation of precontracted isolated bovine lingual artery.
• Uses: 2′-Deoxyguanosine monohydrate has been used in stromal cell purification. It has also been used for the quantification of whole cell dNTP (deoxyribonucleotide triphosphate).