(E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate

Base Information

• Chemical Name: (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate
• CAS No.: 1416426-63-5
• Molecular Formula: C₁₆H₁₈NO₅PS
• Molecular Weight: 367.362
• Mol file: 1416426-63-5.mol

Synonyms:(E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate

Chemical Property of (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate

There total 3 articles about (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C16H19ClNO5PS → (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate (1416426-63-5)

Guidance literature:

With poly(4-vinylpyridine); In dichloromethane; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.9b03669

Reference yield:

dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate (59191-36-5) → (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate (1416426-63-5)

Guidance literature:

Multi-step reaction with 2 steps

1: trichloroisocyanuric acid / dichloromethane / Inert atmosphere

2: poly(4-vinylpyridine) / dichloromethane / 40 °C / Inert atmosphere

With trichloroisocyanuric acid; In dichloromethane;

DOI:10.1002/adsc.201200516

Reference yield:

phenyl N-tosyl imine (51608-60-7) → (E)-dimethyl (4-methylphenylsulfonamido)(phenyl)methylphosphonate (1416426-63-5)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / toluene / Reflux; Inert atmosphere

2: trichloroisocyanuric acid / dichloromethane / Inert atmosphere

3: poly(4-vinylpyridine) / dichloromethane / 40 °C / Inert atmosphere

With trichloroisocyanuric acid; triethylamine; In dichloromethane; toluene;

DOI:10.1002/adsc.201200516

upstream raw materials:

phenyl N-tosyl imine

dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate

Downstream raw materials:

(S)-dimethyl (cyano(4-methylphenylsulfonamido)(phenyl)methyl)phosphonate

dimethyl (((4-methylphenyl)sulfonamido)(phenyl)methyl)phosphonate