tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide

Base Information

• Chemical Name: tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide
• CAS No.: 101924-93-0
• Molecular Formula: C₂₂H₃₅N₅O₅
• Molecular Weight: 449.55
• Mol file: 101924-93-0.mol

Synonyms:tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide

Chemical Property of tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide

There total 1 articles about tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.5%

Boc-Gln-OH (13726-85-7) + H-Leu-NHNHPh*TFA (77162-15-3) → tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide (101924-93-0)

Guidance literature:

With papain; In water; at 37 ℃; for 24h; acetate buffer, pH 4.8; ethylenediaminetetraacetic acid, cysteine hydrochloride;

Reference yield:

tert-butyloxycatbonylglutaminyl-leucine phenylhydrazide (101924-93-0) → pyroglutamyl-leucine phenylhydrazide (101924-97-4)

Guidance literature:

With trifluoroacetic acid; papain; Yield given. Multistep reaction; 2. aq. NaOH, pH 7.5, 37 deg C, 2 h;

upstream raw materials:

Boc-Gln-OH

H-Leu-NHNHPh*TFA

Downstream raw materials:

pyroglutamyl-leucine phenylhydrazide