N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL

Base Information

• Chemical Name: N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL
• CAS No.: 2159-18-4
• Molecular Formula: C₆H₁₄O
• Molecular Weight: 113.089
• Mol file: 2159-18-4.mol

Synonyms:N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL

Chemical Property of N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL

Chemical Property:

• PSA: 20.23000
• LogP: 1.55900

Purity/Quality:

99% ^*data from raw suppliers

1-Hexanol-d11 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Hexanol-d11 is the labelled analogue of 1-Hexanol (H281220), a perturbing agent on actomyosin ATPase and and was found to modulate the function of actomyosin motor via intermediate-specific structural perturbation.

Technology Process of N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL

There total 2 articles about N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

6,6,6,5,5,4,4,3,3,2,2-d11-hexanoic acid (95348-44-0) → hexan-2,2,3,3,4,4,5,5,6,6,6-2H11-1-ol (2159-18-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Reflux; Inert atmosphere;

DOI:10.1039/d1cc02475b

Reference yield:

→ hexan-2,2,3,3,4,4,5,5,6,6,6-2H11-1-ol (2159-18-4)

Guidance literature:

aus Aethyl-perdeuterohexanat, LiAlH4;

DOI:10.1002/jlcr.2590010107

Reference yield:

hexan-2,2,3,3,4,4,5,5,6,6,6-2H11-1-ol (2159-18-4) → 1-(3-(pentyl-2H11)oxiran-2-yl)-2-(triphenyl-λ5-phosphanylidene)ethan-1-one

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: sodium hydride / acetonitrile / 3 h / -30 - 20 °C / Inert atmosphere

With sodium hydride; pyridinium chlorochromate; In dichloromethane; acetonitrile; 2: |Johnson-Corey-Chaykovsky Reaction;

DOI:10.1039/d1cc02475b

upstream raw materials:

6,6,6,5,5,4,4,3,3,2,2-d₁₁-hexanoic acid

Refernces