2'-Chloro-3'-(trifluoromethyl)acetophenone

Base Information

Chemical Name:2'-Chloro-3'-(trifluoromethyl)acetophenone
CAS No.:129322-82-3
Molecular Formula:C₉H₆ClF₃O
Molecular Weight:222.594
Hs Code.:2914790090
European Community (EC) Number:896-080-7
DSSTox Substance ID:DTXSID701247018
Mol file:129322-82-3.mol

Synonyms:2'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE;129322-82-3;1-[2-chloro-3-(trifluoromethyl)phenyl]ethanone;1-(2-Chloro-3-trifluoromethyl-phenyl)-ethanone;1-[2-chloro-3-(trifluoromethyl)phenyl]ethan-1-one;1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-one;SCHEMBL9524633;IQGXHYRICLUDTC-UHFFFAOYSA-N;DTXSID701247018;MFCD09832253;AKOS015956625;JS-4547;CS-0444315;EN300-6482980

Suppliers and Price of 2'-Chloro-3'-(trifluoromethyl)acetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2'-Chloro-3'-(trifluoromethyl)acetophenone
5 g
$ 112.00

SynQuest Laboratories
2'-Chloro-3'-(trifluoromethyl)acetophenone
25 g
$ 397.00

Matrix Scientific
2'-Chloro-3'-(trifluoromethyl)acetophenone
5g
$ 147.00

Matrix Scientific
2'-Chloro-3'-(trifluoromethyl)acetophenone
25g
$ 588.00

Crysdot
2'-Chloro-3'-(trifluoromethyl)acetophenone 95+%
25g
$ 542.00

American Custom Chemicals Corporation
2'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE 95.00%
5MG
$ 500.82

Alichem
2'-Chloro-3'-(trifluoromethyl)acetophenone
1g
$ 1549.60

Alichem
2'-Chloro-3'-(trifluoromethyl)acetophenone
500mg
$ 839.45

Alichem
2'-Chloro-3'-(trifluoromethyl)acetophenone
250mg
$ 475.20

Total 7 raw suppliers

Chemical Property of 2'-Chloro-3'-(trifluoromethyl)acetophenone

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:222.0059270
Heavy Atom Count:14
Complexity:227

Purity/Quality:

98% ^*data from raw suppliers

2'-Chloro-3'-(trifluoromethyl)acetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=C(C(=CC=C1)C(F)(F)F)Cl

Technology Process of 2'-Chloro-3'-(trifluoromethyl)acetophenone

There total 6 articles about 2'-Chloro-3'-(trifluoromethyl)acetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 62584-32-1
2-chloro-3-trifluoromethylbenzonitrile

: 129322-82-3
1-<2-chloro-3-(trifluoromethyl)phenyl>ethanone

Guidance literature:: With methylmagnesium bromide;

Reference yield:

: 88-16-4
1-chloro-2-(trifluoromethyl)benzene

: 129322-82-3
1-<2-chloro-3-(trifluoromethyl)phenyl>ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / 1.6 M n-BuLi / tetrahydrofuran; hexane / -78 deg C, 30 min; -78 to 5 deg C

2: 1.) SOCl₂, DMF, 2.) 2N HCl, 3.) H₂O, cc. H₂SO₄, AcOH / 1.) 1 h, reflux, 2.) Et₂O; 20 min, reflux, 3.) 2 h, reflux

With hydrogenchloride; n-butyllithium; thionyl chloride; sulfuric acid; water; acetic acid; N,N-dimethyl-formamide; In tetrahydrofuran; hexane;