1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose

Base Information

• Chemical Name: 1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose
• CAS No.: 1407180-91-9
• Molecular Formula: C₃₀H₅₈O₄Si₃
• Molecular Weight: 567.045
• Mol file: 1407180-91-9.mol

Synonyms:1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose

Chemical Property of 1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose

There total 1 articles about 1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1β-(2-bromobenzyl)-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose (1407180-88-4) → 1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose (1407180-91-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; triethylamine; In tetrahydrofuran; ethanol; water; at 20 ℃; for 12h; under 757.576 Torr;

DOI:10.1002/ejoc.201200819

Reference yield: 80.0%

1β-benzyl-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose (1407180-91-9) → 1β-(2-benzyl)-1-deoxy-D-ribofuranose (1407181-01-4,500894-21-3)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; at 40 ℃; for 48h;

DOI:10.1002/ejoc.201200819

upstream raw materials:

1β-(2-bromobenzyl)-2,3,5-tri-O-(tert-butyldimethylsilyl)-1-deoxy-D-ribofuranose

Downstream raw materials:

1β-(2-benzyl)-1-deoxy-D-ribofuranose