Technology Process of 4-pentenyl 3,4-di-O-benzyl-2-O-chloroacetyl-6-deoxy-α-L-talopyranoside
There total 10 articles about 4-pentenyl 3,4-di-O-benzyl-2-O-chloroacetyl-6-deoxy-α-L-talopyranoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine;
In
dichloromethane;
cooling;
DOI:10.1021/jo030304e
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: p-toluenesulfonic acid monohydrate / 36 h / 95 °C
2.1: 2.1 g / CH2Cl2 / 24 h / 20 °C
3.1: 88 percent / PCC; 4 Angstroem molecular sieves / CH2Cl2 / 20 °C
4.1: 93 percent / sodium borohydride / aq. ethanol / 2 h / 20 °C
5.1: NaOH / dioxane / 80 °C
6.1: 3.5 g / aq. AcOH / 1 h / 50 °C
7.1: Bu2SnO / benzene / 24 h / Heating
7.2: 41 percent / Bu4NBr / benzene / 24 h / Heating
8.1: 91 percent / pyridine / CH2Cl2 / cooling
With
pyridine; sodium hydroxide; sodium tetrahydroborate; 4 A molecular sieve; di(n-butyl)tin oxide; toluene-4-sulfonic acid; acetic acid; pyridinium chlorochromate;
In
1,4-dioxane; ethanol; dichloromethane; benzene;
DOI:10.1021/jo030304e
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: p-toluenesulfonic acid monohydrate / 36 h / 95 °C
2.1: 2.1 g / CH2Cl2 / 24 h / 20 °C
3.1: 88 percent / PCC; 4 Angstroem molecular sieves / CH2Cl2 / 20 °C
4.1: 93 percent / sodium borohydride / aq. ethanol / 2 h / 20 °C
5.1: NaOH / dioxane / 80 °C
6.1: 3.5 g / aq. AcOH / 1 h / 50 °C
7.1: Bu2SnO / benzene / 24 h / Heating
7.2: 41 percent / Bu4NBr / benzene / 24 h / Heating
8.1: 91 percent / pyridine / CH2Cl2 / cooling
With
pyridine; sodium hydroxide; sodium tetrahydroborate; 4 A molecular sieve; di(n-butyl)tin oxide; toluene-4-sulfonic acid; acetic acid; pyridinium chlorochromate;
In
1,4-dioxane; ethanol; dichloromethane; benzene;
DOI:10.1021/jo030304e
