Technology Process of C15H20ClNO4
There total 4 articles about C15H20ClNO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
for 1.5h;
Reflux;
DOI:10.1021/ol2018455
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide / methanol / 1.5 h / Reflux
2: oxalyl dichloride / N,N-dimethyl-formamide / 4 h / 0 °C
With
oxalyl dichloride; sodium hydroxide;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/acs.orglett.8b00283
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 8 h / 110 °C
2.1: nitric acid; sulfuric acid / 0.83 h / -25 °C
3.1: sodium hydroxide / methanol; water / 1.5 h / Reflux
3.2: pH 2
4.1: oxalyl dichloride / dichloromethane / 4 h / 0 °C
With
oxalyl dichloride; sulfuric acid; nitric acid; potassium carbonate; potassium iodide; sodium hydroxide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jacs.9b06094