N₁-hydroxy-N₄-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride

Base Information

• Chemical Name: N₁-hydroxy-N₄-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride
• CAS No.: 1143460-24-5
• Molecular Formula: C₂₂H₁₇N₅O₃S*ClH
• Molecular Weight: 467.936

Synonyms:N₁-hydroxy-N₄-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride

Chemical Property of N₁-hydroxy-N₄-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride

Chemical Property:

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Technology Process of N₁-hydroxy-N₄-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride

There total 2 articles about N₁-hydroxy-N₄-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

N1-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)-N4-(tetrahydro-2H-pyran-2-yloxy)terephthalamide (1143460-21-2) → N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride (1143460-24-5)

Guidance literature:

With hydrogenchloride; In methanol; water; at 20 ℃; for 16h;

DOI:10.1021/jm800988r

Reference yield: 70.0%

→ N1-hydroxy-N4-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)terephthalamide hydrochloride (1143460-24-5)

Guidance literature:

upstream raw materials:

N₁-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)-N₄-(tetrahydro-2H-pyran-2-yloxy)terephthalamide

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