N₆-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide

Base Information

• Chemical Name: N₆-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide
• CAS No.: 417720-81-1
• Molecular Formula: C₂₇H₃₂ClN₅O₄
• Molecular Weight: 526.035

Synonyms:N₆-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide

Chemical Property of N₆-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide

Chemical Property:

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Technology Process of N₆-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide

There total 1 articles about N₆-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N6-ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide (417720-79-7) + tert-butyl 4-(bromomethyl)piperidine-1-carboxylate (158407-04-6) → N6-Ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-((1-methyl-4-piperidyl)methoxy)-6-quinolinecarboxamide (417720-81-1)

Guidance literature:

With formaldehyd; sodium cyanoborohydride; potassium carbonate; acetic acid; triethylamine; In N-methyl-acetamide; methanol; tetrahydrofuran (2 ML)-methanol; ethyl acetate; trifluoroacetic acid;

upstream raw materials:

N₆-ethyl-4-(3-chloro-4-(((methylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide

tert-butyl 4-(bromomethyl)piperidine-1-carboxylate

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