2-N-HEXADECYLSTEARIC ACID

Base Information

• Chemical Name: 2-N-HEXADECYLSTEARIC ACID
• CAS No.: 89547-15-9
• Molecular Formula: C₃₄H₆₈O₂
• Molecular Weight: 508.913
• Hs Code.: 2915900090
• Mol file: 89547-15-9.mol

Synonyms:2-Hexadecyloctadecanoicacid; 2-Palmitylstearic acid

Chemical Property of 2-N-HEXADECYLSTEARIC ACID

Chemical Property:

• Melting Point: 79 °C
• Boiling Point: 350 °C / 2.5mmHg
• PKA: 4.79±0.40(Predicted)
• Flash Point: 341.2oC
• PSA: 37.30000
• Density: 0.870±0.06 g/cm3(Predicted)
• LogP: 12.43000
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Hexadecyloctadecanoic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Hexadecyl-octadecanoic Acid is a branched saturated fatty acid.

Technology Process of 2-N-HEXADECYLSTEARIC ACID

There total 8 articles about 2-N-HEXADECYLSTEARIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

1-iodohexadecane (544-77-4) + stearic acid (57-11-4) → 2-hexadecyloctadecanoic acid (89547-15-9)

Guidance literature:

stearic acid; With sodium hydride; lithium diisopropyl amide; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

1-iodohexadecane; In tetrahydrofuran; mineral oil; at 45 ℃; for 6h; Inert atmosphere;

DOI:10.1021/jm3016443

Reference yield:

dihexadecylmalonic acid (4471-14-1) → 2-hexadecyloctadecanoic acid (89547-15-9)

Guidance literature:

at 170 ℃; im Vakuum;

Reference yield:

hexadecanyl bromide (112-82-3) → 2-hexadecyloctadecanoic acid (89547-15-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / 5,5-dimethyl-1,3-cyclohexadiene

1.2: 10 h / Reflux

2.1: sodium hydroxide / ethanol

3.1: hydrogenchloride / water / 200 °C

With hydrogenchloride; sodium hydride; sodium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; ethanol; water;

DOI:10.1016/j.ejpb.2015.08.011

upstream raw materials:

dihexadecylmalonic acid

1-iodohexadecane

stearic acid

hexadecanyl bromide

Downstream raw materials:

6,6'-bis-O-(2-hexadecyloctadecanoyl)-2,3,4,2',3',4'-hexabenzyl-α,α'-trehalose

2-Hexadecyloctadecan-1-ol