1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Base Information

Chemical Name:1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate
CAS No.:1351556-90-5
Molecular Formula:C₃₈H₄₂FN₇O₉
Molecular Weight:759.791
Hs Code.:

1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Synonyms:1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Suppliers and Price of 1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

There total 3 articles about 1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: prop-2-yn-1-yl 4-fluorobenzoate

: 1024017-21-7
C₂₈H₃₅N₇O₇

: 1351556-90-5
1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; at 20 ℃; for 21h;
DOI:10.1021/jm201142w

Reference yield:

: 5-bromo-5-(4-phenoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione

: 1351556-90-5
1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 5 - 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; N,N-dimethyl-formamide / 21 h / 20 °C

With copper(ll) sulfate pentahydrate; potassium carbonate; sodium L-ascorbate; In water; N,N-dimethyl-formamide;
DOI:10.1021/jm201142w

Reference yield:

: 219311-20-3
5-(4-phenoxyphenyl)pyrimidine-2,4,6-trione

: 1351556-90-5
1-(2-{2-[2-(2-{4-[2,4,6-trioxo-5-(4-phenoxyphenyl)hexahydropyrimidin-5-yl]piperazin-1-yl}ethoxy)ethoxy]ethoxy}ethyl)-1H-1,2,3-triazol-4-yl-methyl 4-fluorobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide / N,N-dimethyl-formamide / 0.33 h / 5 - 10 °C

2: potassium carbonate / N,N-dimethyl-formamide / 5 - 20 °C

3: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; N,N-dimethyl-formamide / 21 h / 20 °C

With N-Bromosuccinimide; copper(ll) sulfate pentahydrate; potassium carbonate; sodium L-ascorbate; In water; N,N-dimethyl-formamide;
DOI:10.1021/jm201142w