Tris(4-methoxy-3,5-dimethylphenyl)phosphine

Base Information

• Chemical Name: Tris(4-methoxy-3,5-dimethylphenyl)phosphine
• CAS No.: 121898-64-4
• Molecular Formula: C₂₇H₃₃O₃P
• Molecular Weight: 436.531
• European Community (EC) Number: 634-225-6
• DSSTox Substance ID: DTXSID40405156
• Nikkaji Number: J209.086D
• Wikidata: Q72515225
• Mol file: 121898-64-4.mol

Synonyms:TRIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINE;121898-64-4;tris(4-methoxy-3,5-dimethylphenyl)phosphane;Phosphine, tris(4-methoxy-3,5-dimethylphenyl)-;MFCD03840342;SCHEMBL897369;DTXSID40405156;WEA89864;AKOS015910214;CS-W014454;AS-66947;FT-0744628;TRIS(3,5-DIMETHYL-4-METHOXY)PHOSPHINE;A891301;Tris(4-methoxy-3,5-dimethylphenyl)phosphine, 97%

Chemical Property of Tris(4-methoxy-3,5-dimethylphenyl)phosphine

Chemical Property:

• Melting Point: 175-177°C
• Boiling Point: 539.3±50.0 °C(Predicted)
• PSA: 41.28000
• LogP: 5.32100
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 6.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 436.21673191
• Heavy Atom Count: 31
• Complexity: 445

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tris(4-methoxy-3,5-dimethylphenyl)phosphine, min. 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1OC)C)P(C2=CC(=C(C(=C2)C)OC)C)C3=CC(=C(C(=C3)C)OC)C
• Uses: Catalyst for carbocyanation of alkynes

Technology Process of Tris(4-methoxy-3,5-dimethylphenyl)phosphine

There total 2 articles about Tris(4-methoxy-3,5-dimethylphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

5-bromo-2-methoxy-1,3-dimethylbenzene (14804-38-7) → tris(4-methoxy-3,5-bis-dimethylphenyl)phosphine (121898-64-4)

Guidance literature:

5-bromo-2-methoxy-1,3-dimethylbenzene; With iodine; magnesium; In tetrahydrofuran; at 20 ℃; for 1.5h; Inert atmosphere;

With phosphorus trichloride; In tetrahydrofuran; at 20 ℃; for 1.33333h; Inert atmosphere;

DOI:10.1246/bcsj.20210023

Reference yield:

triphenyl phosphite (101-02-0) + 5-bromo-2-methoxy-1,3-dimethylbenzene (14804-38-7) → tris(4-methoxy-3,5-bis-dimethylphenyl)phosphine (121898-64-4)

Guidance literature:

With magnesium; In tetrahydrofuran;

upstream raw materials:

triphenyl phosphite

5-bromo-2-methoxy-1,3-dimethylbenzene

Refernces

• 1、 -. "Catalyst for polymerization of conjugated diene and process for producing conjugated diene polymer". . . Retrieved 2008/06/13.