N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

Base Information

Chemical Name:N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride
CAS No.:925929-98-2
Molecular Formula:C₂₇H₂₂FN₅O₄*ClH
Molecular Weight:535.962
Hs Code.:

Synonyms:N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

Suppliers and Price of N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

There total 1 articles about N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 925924-01-2
tert-butyl {3-[(3-{3-cyano-6-[4-fluoro-2-(methoxymethoxy)phenyl]-2-[(furan-2-ylcarbonyl)amino]pyridin-4-yl}phenyl)amino]-3-oxopropyl}methylcarbamate

: 925929-98-2
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 20 ℃; for 40h;
DOI:10.1016/j.bmc.2010.05.061

Reference yield:

: 925929-98-2
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride

: 75-07-0,9002-91-9
acetaldehyde

: 925981-40-4
N-[3-cyano-4-{3-[(N-ethyl-N-methyl-β-alanyl)amino]phenyl}-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide

Guidance literature:: N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-methyl-β-alanyl)amino]phenyl}pyridin-2-yl]furan-2-carboxamide hydrochloride; acetaldehyde; With sodium cyanoborohydride; acetic acid; In methanol; at 20 ℃; for 4h;

With sodium hydrogencarbonate; In methanol; water;
DOI:10.1016/j.bmc.2010.05.061