Technology Process of C15H16BNO3*ClH
There total 6 articles about C15H16BNO3*ClH which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / N,N-dimethyl-formamide / 80 °C
2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / 1,4-dioxane / 90 °C
3: sodium tetrahydroborate / methanol / 1 h / 0 - 20 °C
4: hydrogenchloride / water
5: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C
With
hydrogenchloride; sodium tetrahydroborate; lithium aluminium tetrahydride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate; potassium carbonate;
In
tetrahydrofuran; 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
2: |Miyaura Borylation Reaction;
DOI:10.1016/j.bmcl.2013.01.072
- Guidance literature:
-
C15H12BNO3;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 1h;
With
hydrogenchloride;
In
1,4-dioxane;
DOI:10.1016/j.bmcl.2013.01.072
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / 1 h / 0 - 20 °C
2: hydrogenchloride / water
3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C
With
hydrogenchloride; sodium tetrahydroborate; lithium aluminium tetrahydride;
In
tetrahydrofuran; methanol; water;
DOI:10.1016/j.bmcl.2013.01.072
