(1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

Base Information

Chemical Name:(1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide
CAS No.:905916-07-6
Molecular Formula:C₂₀H₂₄N₂O₂
Molecular Weight:324.423
Hs Code.:

Synonyms:(1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

Suppliers and Price of (1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

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Technology Process of (1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

There total 2 articles about (1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 905916-03-2
(1S,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarbonitrile

: 905916-07-6
(1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

Guidance literature:: With potassium hydroxide; dihydrogen peroxide; In ethanol; water; at 0 - 20 ℃;
DOI:10.1016/j.tetasy.2006.05.014

Reference yield:

: 905916-00-9
(1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarbonitrile

: 905916-07-6
(1R,2R,1'S)-2-benzyloxy-1-[(1'-phenylethyl)amino]cyclobutanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / ZnBr₂ / dimethylsulfoxide / 72 h / 45 °C

2: 75 percent / potassium hydroxide; hydrogen peroxide / ethanol; H₂O / 0 - 20 °C

With potassium hydroxide; dihydrogen peroxide; zinc dibromide; In ethanol; water; dimethyl sulfoxide;
DOI:10.1016/j.tetasy.2006.05.014