methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

Base Information

Chemical Name:methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate
CAS No.:945915-86-6
Molecular Formula:C₂₅H₂₉N₃O₃
Molecular Weight:419.524
Hs Code.:

Synonyms:methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

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Chemical Property of methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

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Technology Process of methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

There total 2 articles about methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₃₁N₃O₄

: 945915-86-6
methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

Guidance literature:: With acetic acid; In 1,2-dichloro-ethane; at 80 ℃; for 1h; Product distribution / selectivity;

Reference yield:

: 809237-70-5
methyl {3-amino-4-[(cyclohexylmethyl)amino]phenyl}carbamate

: 69999-16-2
2,3-dihydrobenzofuran-5-acetic acid

: 945915-86-6
methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

Guidance literature:: methyl {3-amino-4-[(cyclohexylmethyl)amino]phenyl}carbamate; 2,3-dihydrobenzofuran-5-acetic acid; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 17 - 25 ℃;

With hydrogenchloride; at 80 ℃; Product distribution / selectivity;

Reference yield: 27.0%

: 945915-86-6
methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate

: 1-(cyclohexylmethyl)-2-(2,3-dihydro-benzofuran-5-ylmethyl)-N-methyl-1H-benzoimidazol-5-amine

Guidance literature:: methyl [1-cyclohexylmethyl-2-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-benzoimidazol-5-yl]carbamate; With hydrogenchloride; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.25h;

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 0 - 25 ℃;

With methanol; water; In tetrahydrofuran; diethyl ether; at 17 - 25 ℃; for 0.75h;