10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one

Base Information

Chemical Name:10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one
CAS No.:1448520-16-8
Molecular Formula:C₂₂H₃₁NO₄
Molecular Weight:373.492
Hs Code.:

Synonyms:10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one

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Chemical Property of 10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one

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Technology Process of 10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one

There total 2 articles about 10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1448520-15-7
10-ethyl-11-oxa-3-azaspiro[5.5]undecan-8-one

: 854631-20-2
4-isopropoxy-3-methylbenzoyl chloride

: 1448520-16-8
10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

: 1448520-36-2
benzyl 8-oxo-10-vinyl-11-oxa-3-azaspiro[5.5]undecane-3-carboxylate

: 1448520-16-8
10-ethyl-3-(4-isopropoxy-3-methylbenzoyl)-11-oxa-3-azaspiro[5.5]undecan-8-one

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon / methanol / Inert atmosphere

2: triethylamine / dichloromethane / 20 °C

With palladium 10% on activated carbon; triethylamine; In methanol; dichloromethane;