ethyl 6-chloro-3-cyano-4-(4-methoxyphenyl)-4H-benzo[h]chromen-2-yliminoformate

Base Information

• Chemical Name: ethyl 6-chloro-3-cyano-4-(4-methoxyphenyl)-4H-benzo[h]chromen-2-yliminoformate
• CAS No.: 162378-41-8
• Molecular Formula: C₂₄H₁₉ClN₂O₃
• Molecular Weight: 418.879
• Mol file: 162378-41-8.mol

Synonyms:6-chloro-2-ethoxymethylideneamino-4-(p-methoxyphenyl)-4H-naphtho[1,2-b]pyran-3-carbonitrile

Chemical Property of ethyl 6-chloro-3-cyano-4-(4-methoxyphenyl)-4H-benzo[h]chromen-2-yliminoformate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 6-chloro-3-cyano-4-(4-methoxyphenyl)-4H-benzo[h]chromen-2-yliminoformate

There total 1 articles about ethyl 6-chloro-3-cyano-4-(4-methoxyphenyl)-4H-benzo[h]chromen-2-yliminoformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

orthoformic acid triethyl ester (122-51-0) + 2-amino-6-chloro-4-(4-methoxyphenyl)-4H-benzo[h]chromene-3-carbonitrile → 6-chloro-2-ethoxymethylideneamino-4-(p-methoxyphenyl)-4H-naphtho[1,2-b]pyran-3-carbonitrile (162378-41-8)

Guidance literature:

With acetic anhydride; for 5h; Heating;

Reference yield: 87.0%

6-chloro-2-ethoxymethylideneamino-4-(p-methoxyphenyl)-4H-naphtho[1,2-b]pyran-3-carbonitrile (162378-41-8) → 5-chloro-8-imino-7-(p-methoxyphenyl)-8,9-dihydro-7H-naphtho[2',1':5,6]pyrano[2,3-d]pyrimidin-9-amine (162378-42-9)

Guidance literature:

With hydrazine hydrate; In ethanol; for 0.75h;

Reference yield:

6-chloro-2-ethoxymethylideneamino-4-(p-methoxyphenyl)-4H-naphtho[1,2-b]pyran-3-carbonitrile (162378-41-8) → 12-chloro-14-(p-methoxyphenyl)-14H-naphtho[2',1':5,6]pyrano[2,3-e]-1,2,4-triazolo[2,3-c]pyrimidine

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / hydrazine hydrate / ethanol / 0.75 h

2: 50 percent / 8 h / Heating

With hydrazine hydrate; In ethanol;

upstream raw materials:

orthoformic acid triethyl ester

Downstream raw materials:

5-chloro-8-imino-7-(p-methoxyphenyl)-8,9-dihydro-7H-naphtho[2',1':5,6]pyrano[2,3-d]pyrimidin-9-amine