C₂₃H₂₃NO₅S

Base Information

• Chemical Name: C₂₃H₂₃NO₅S
• CAS No.: 1333378-27-0
• Molecular Formula: C₂₃H₂₃NO₅S
• Molecular Weight: 425.505
• Mol file: 1333378-27-0.mol

Synonyms:C₂₃H₂₃NO₅S

Chemical Property of C₂₃H₂₃NO₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₃NO₅S

There total 6 articles about C₂₃H₂₃NO₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C32H43NO5SSi (1333378-26-9) → C23H23NO5S (1333378-27-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; water; at 0 ℃; for 0.333333h;

DOI:10.1002/ejoc.201100242

Reference yield:

C12H10BrNO4 (1333378-22-5) → C23H23NO5S (1333378-27-0)

Guidance literature:

Multi-step reaction with 5 steps

1: dmap; triethylamine / dichloromethane / 2 h / 0 °C

2: sodium tetrahydroborate / methanol / 0 - 20 °C

3: camphor-10-sulfonic acid / dichloromethane / 0 - 20 °C

4: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / 1,4-dioxane / 21 h / 100 °C

5: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.33 h / 0 °C

With dmap; sodium tetrahydroborate; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 4: Sonogashira coupling;

DOI:10.1002/ejoc.201100242

Reference yield:

C19H16BrNO6S (1333378-23-6) → C23H23NO5S (1333378-27-0)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium tetrahydroborate / methanol / 0 - 20 °C

2: camphor-10-sulfonic acid / dichloromethane / 0 - 20 °C

3: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / 1,4-dioxane / 21 h / 100 °C

4: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.33 h / 0 °C

With sodium tetrahydroborate; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 3: Sonogashira coupling;

DOI:10.1002/ejoc.201100242

upstream raw materials:

C₁₂H₁₀BrNO₄

C₁₉H₁₆BrNO₆S

C₁₈H₁₈BrNO₅S

C₂₁H₂₂BrNO₅S

Downstream raw materials:

C₂₄H₂₄BrNO₇S

C₃₅H₃₅N₃O₈S₂

C₂₄H₂₃NO₇S