Palladium(II) trifluoroacetate

Base Information

• Chemical Name: Palladium(II) trifluoroacetate
• CAS No.: 42196-31-6
• Molecular Formula: C4F6O4Pd
• Molecular Weight: 332.45
• Hs Code.: 28439000
• European Community (EC) Number: 628-066-1
• DSSTox Substance ID: DTXSID50369856
• Nikkaji Number: J1.053.953F
• Mol file: 42196-31-6.mol

Synonyms:Palladium(II) trifluoroacetate;42196-31-6;Palladium(II) 2,2,2-trifluoroacetate;palladium(2+);2,2,2-trifluoroacetate;Trifluoroacetic acid palladium(II) salt;palladium(2+) ion ditrifluoroacetate;PALLADIUM TRIFLUOROACETATE;BIS(2,2,2-TRIFLUOROACETOXY)PALLADIUM;C4F6O4Pd;Palladium(II)trifluoroacetate;palladium(II)trifluoro-acetate;SCHEMBL204190;palladium bis(trifluoroacetate);palladium (II) trifluoroacetate;trifluoroacetate palladium (II);DTXSID50369856;PBDBXAQKXCXZCJ-UHFFFAOYSA-L;bis(trifluoroacetoxy)palladium (II);bis(trifluoroacetoxy) palladium (II);Palladium(2+) bis(trifluoroacetate);AKOS015852670;GS-6670;SC10438;FT-0639771;P1870;A825802;EN300-19320105;Acetic acid, 2,2,2-trifluoro-, palladium(2+) salt (2:1);Palladium(II) trifluoroacetate, =99.95% Trace metals grade;PALLADIUM(II) TRIFLUOROACETATE;PD(TFA)2;TRIFLUOROACETIC ACID PALLADIUM(II) SALT

Chemical Property of Palladium(II) trifluoroacetate

Chemical Property:

• Appearance/Colour: tan to brown powder
• Vapor Pressure: 96.2mmHg at 25°C
• Melting Point: ~220 °C
• Boiling Point: 72.2 °C at 760 mmHg
• PSA: 52.60000
• LogP: 1.11240
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: Soluble in diethyl ether and acetone. Insoluble in benzene, chlo
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 0
• Exact Mass: 331.87356
• Heavy Atom Count: 15
• Complexity: 77.9

Purity/Quality:

99% ^*data from raw suppliers

Palladium(II) Trifluoroacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C(F)(F)F)[O-].C(=O)(C(F)(F)F)[O-].[Pd+2]
• Uses: Palladium(II) Trifluoroacetate is a pallaium salt of Trifluoroacetic Acid (T786035), a solvent used in a variety of organic synthesis and chemical processes. Also used in the synthesis of anticancer agents as well as phospholipase D inhibitors.

Refernces

Synthesis of 2-Arylindoles through Pd(II)-Catalyzed Cyclization of Anilines with Vinyl Azides

10.1021/acs.joc.8b01618

Lianghua Jie et al. presents a novel and efficient method for synthesizing 2-arylindoles using a Pd(II)-catalyzed cyclization reaction. The study explores the use of vinyl azides as versatile coupling partners with anilines, achieving high efficiency and excellent regioselectivity under mild reaction conditions. Pd(TFA)2 (Palladium(II) trifluoroacetate) is a commonly used palladium catalyst in organic synthesis. It is particularly effective in C—H activation and cross-coupling reactions. In this study, it facilitates the cyclization reaction by activating the C—H bond of the aniline substrate, allowing for the formation of the desired 2-arylindole product. This work provides a straightforward and functional group-tolerant approach to synthesizing 2-arylindoles, which are important scaffolds in natural products and pharmaceuticals.