Technology Process of C20(13)CH24BrNO
There total 4 articles about C20(13)CH24BrNO which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 25 ℃;
for 20h;
Inert atmosphere;
DOI:10.1021/ol4003465
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium trimethylsilonate; bis(dibenzylideneacetone)-palladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / toluene / 0.33 h / 40 °C
2: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 25 °C / Inert atmosphere
With
4-methyl-morpholine; potassium trimethylsilonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium(0);
In
dichloromethane; toluene;
DOI:10.1021/ol4003465
- Guidance literature:
-
Multi-step reaction with 3 steps
1: nitric acid / acetic anhydride / 1.5 h / 0 - 20 °C
2: palladium 10% on activated carbon; ammonium formate / methanol / 2 h / Reflux
3: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 25 °C / Inert atmosphere
With
4-methyl-morpholine; palladium 10% on activated carbon; nitric acid; ammonium formate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
methanol; dichloromethane; acetic anhydride;
DOI:10.1021/ol4003465
