Technology Process of cyclohexyl-2,2,6,6-d4-methyl triflate
There total 4 articles about cyclohexyl-2,2,6,6-d4-methyl triflate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,6-dimethylpyridine;
In
Petroleum ether;
at 0 ℃;
for 1h;
DOI:10.1021/ja00392a031
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 55 percent / NaH / dimethylsulfoxide / 1.) 75 - 80 deg C, 45 min, 2.) room temperature, 10 min
2: 52 percent / boron trifluoride etherate, LiAlH4 / diethyl ether / 2 h / Ambient temperature
3: 68 percent / 2,6-lutidine / petroleum ether / 1 h / 0 °C
With
2,6-dimethylpyridine; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; sodium hydride;
In
diethyl ether; dimethyl sulfoxide; Petroleum ether;
DOI:10.1021/ja00392a031
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 52 percent / boron trifluoride etherate, LiAlH4 / diethyl ether / 2 h / Ambient temperature
2: 68 percent / 2,6-lutidine / petroleum ether / 1 h / 0 °C
With
2,6-dimethylpyridine; lithium aluminium tetrahydride; boron trifluoride diethyl etherate;
In
diethyl ether; Petroleum ether;
DOI:10.1021/ja00392a031
