1-(tert-Butoxycarbonyl)-3-ethyl-3-piperidinecarboxylic acid

Base Information

• Chemical Name: 1-(tert-Butoxycarbonyl)-3-ethyl-3-piperidinecarboxylic acid
• CAS No.: 887591-65-3
• Molecular Formula: C₁₃H₂₃NO₄
• Molecular Weight: 257.33
• Mol file: 887591-65-3.mol

Synonyms:1-(1,1-dimethylethyl)-3-ethyl-1,3-piperidinedicarboxylate

Chemical Property of 1-(tert-Butoxycarbonyl)-3-ethyl-3-piperidinecarboxylic acid

Chemical Property:

• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

1-Boc-3-Ethylpiperidine-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(tert-Butoxycarbonyl)-3-ethyl-3-piperidinecarboxylic acid

There total 1 articles about 1-(tert-Butoxycarbonyl)-3-ethyl-3-piperidinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + Ethyl nipecotate (71962-74-8) → 1-(1,1-dimethylethyl)-3-ethyl-1,3-piperidinedicarboxylate (887591-65-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 4h;

Reference yield:

1-(1,1-dimethylethyl)-3-ethyl-1,3-piperidinedicarboxylate (887591-65-3) → Ethyl nipecotate (71962-74-8)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at -78 ℃; for 2h;

upstream raw materials:

di-tert-butyl dicarbonate

Ethyl nipecotate

Downstream raw materials:

Ethyl nipecotate

Refernces