benzyl 2-acetoxy-4-hydroxyphenyl ketone

Base Information

• Chemical Name: benzyl 2-acetoxy-4-hydroxyphenyl ketone
• CAS No.: 145747-27-9
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.285
• Mol file: 145747-27-9.mol

Synonyms:benzyl 2-acetoxy-4-hydroxyphenyl ketone

Chemical Property of benzyl 2-acetoxy-4-hydroxyphenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of benzyl 2-acetoxy-4-hydroxyphenyl ketone

There total 4 articles about benzyl 2-acetoxy-4-hydroxyphenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-(2,4-diacetoxyphenyl)-2-phenylethanone (22665-91-4) → benzyl 2-acetoxy-4-hydroxyphenyl ketone (145747-27-9)

Guidance literature:

In tetrahydrofuran; porcine pancreatic lipase (PPL);

Reference yield: 50.0%

1-acetoxy-1-(2,4-diacetoxyphenyl)-2-phenylethene (204068-54-2) → 1-(2,4-diacetoxyphenyl)-2-phenylethanone (22665-91-4) + benzyl 2-acetoxy-4-hydroxyphenyl ketone (145747-27-9)

Guidance literature:

With butan-1-ol; porcine pancreatic lipase (Type-II); In tetrahydrofuran; at 42 - 45 ℃; for 72h;

DOI:10.1016/S0968-0896(97)10010-4

Reference yield:

1-(2,4-dihydroxyphenyl)-2-phenylethanone (3669-41-8) → benzyl 2-acetoxy-4-hydroxyphenyl ketone (145747-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 8 percent / conc. H₂SO₄

2: 65 percent / n-butanol / porcine pancreatic lipase (Type-II) / tetrahydrofuran / 48 h / 42 - 45 °C

With sulfuric acid; butan-1-ol; porcine pancreatic lipase (Type-II); In tetrahydrofuran; 1: Acetylation / 2: Deacetylation;

DOI:10.1016/S0968-0896(97)10010-4

upstream raw materials:

1-(2,4-diacetoxyphenyl)-2-phenylethanone

1-acetoxy-1-(2,4-diacetoxyphenyl)-2-phenylethene

1-(2,4-dihydroxyphenyl)-2-phenylethanone