4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

Base Information

Chemical Name:4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide
CAS No.:143585-47-1
Molecular Formula:C20H26 N2 O4 S2
Molecular Weight:422.569
Hs Code.:
European Community (EC) Number:621-962-3
DSSTox Substance ID:DTXSID60456807
Nikkaji Number:J852.914K
Wikidata:Q76416712
Mol file:143585-47-1.mol

Synonyms:143585-47-1;N,N'-((1R,2R)-cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide);(1R,2R)-N,N'-Di-p-tosyl-1,2-cyclohexanediamine;(1R,2R)-(+)-N,N'-Di-p-tosyl-1,2-cyclohexanediamine;4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide;(1R,2R)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]cyclohexane;SCHEMBL3970619;DTXSID60456807;MFCD01321377;(1R,2R)-(+)-N,N inverted exclamation marka-Di-p-tosyl-1,2-cyclohexanediamine;CS-16224;CS-0093704;(1R)-1beta,2alpha-Bis(tosylamino)cyclohexane;D75432;A808088;(1R,2R)-(+)-N,N/'-Di-p-tosyl-1,2-cyclohexanediamine;(1R,2R)-(+)-N,N'-Di-p-tosyl-1,2-cyclohexanediamine, 98%;(1R,2R)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]-cyclohexane;Benzenesulfonamide,N,N'-(1R,2R)-1,2-cyclohexanediylbis[4-methyl-;4-methyl-N-[(1R,2R)-2-(p-tolylsulfonylamino)cyclohexyl]benzenesulfonamide;N,N'-(Rel-(1R,2R)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide);N,N'-[(1R,2R)-Cyclohexane-1,2-diyl]bis(4-methylbenzene-1-sulfonamide);184874-85-9

Suppliers and Price of 4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
(1R,2R)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]cyclohexane 98+%, 98+%ee
100 g
$ 1100.00

SynChem
(1R,2R)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]cyclohexane 98+%, 98+%ee
10 g
$ 180.00

SynChem
(1R,2R)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]cyclohexane 98+%, 98+%ee
5 g
$ 110.00

Sigma-Aldrich
(1R,2R)-(+)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine 98%
1g
$ 103.00

ChemScene
(1R,2R)-N,N'-Di-p-tosyl-1,2-cyclohexanediamine 99.53%
5g
$ 88.00

American Custom Chemicals Corporation
(1R,2R)-1,2-N,N'-BIS[(4-TOLUENE SULFONYL)AMINO]CYCLOHEXANE 95.00%
100G
$ 3759.53

American Custom Chemicals Corporation
(1R,2R)-1,2-N,N'-BIS[(4-TOLUENE SULFONYL)AMINO]CYCLOHEXANE 95.00%
10G
$ 1309.77

American Custom Chemicals Corporation
(1R,2R)-1,2-N,N'-BIS[(4-TOLUENE SULFONYL)AMINO]CYCLOHEXANE 95.00%
5G
$ 921.69

Ambeed
N,N'-((1R,2R)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide) 98%99%ee
100g
$ 924.00

Ambeed
N,N'-((1R,2R)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide) 98%99%ee
25g
$ 308.00

Total 16 raw suppliers

Chemical Property of 4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

Chemical Property:

Melting Point:170-173 ºC(lit.)
Boiling Point:591.4 ºC at 760 mmHg
PKA:11.02±0.40(Predicted)
Flash Point:311.5 ºC
PSA：109.10000
Density:1.33 g/cm³
LogP:5.81480
Storage Temp.:2-8°C
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:422.13339966
Heavy Atom Count:28
Complexity:634

Purity/Quality:

97% ^*data from raw suppliers

(1R,2R)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]cyclohexane 98+%, 98+%ee ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC2CCCCC2NS(=O)(=O)C3=CC=C(C=C3)C
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N[C@@H]2CCCC[C@H]2NS(=O)(=O)C3=CC=C(C=C3)C

Technology Process of 4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

There total 11 articles about 4-methyl-N-[(1R,2R)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 98-59-9
p-toluenesulfonyl chloride

: 32044-22-7,39961-95-0
(1R,2R)-1,2-diaminocyclohexane tartrate

: 143585-47-1
(R,R)-1,2-bis(tosylamino)cyclohexane

Guidance literature:: With triethylamine; In dichloromethane; water; at 20 ℃;
DOI:10.1039/b210285d

Reference yield: 99.0%

: 20439-47-8
(1R,2R)-1,2-diaminocyclohexane

: 104-15-4
toluene-4-sulfonic acid

: 143585-47-1
(R,R)-1,2-bis(tosylamino)cyclohexane

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1039/c5ra18871g

Reference yield: 91.0%

: 20439-47-8
(1R,2R)-1,2-diaminocyclohexane

: 98-59-9
p-toluenesulfonyl chloride

: 143585-47-1
(R,R)-1,2-bis(tosylamino)cyclohexane

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 23 ℃; for 12h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.5b03708