C₁₆H₁₃IO₄

Base Information

• Chemical Name: C₁₆H₁₃IO₄
• CAS No.: 1260148-51-3
• Molecular Formula: C₁₆H₁₃IO₄
• Molecular Weight: 396.181
• Mol file: 1260148-51-3.mol

Synonyms:C₁₆H₁₃IO₄

Chemical Property of C₁₆H₁₃IO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₃IO₄

There total 6 articles about C₁₆H₁₃IO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C17H15IO5 (1260148-63-7) → C16H13IO4 (1260148-51-3)

Guidance literature:

C₁₇H₁₅IO₅; With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃;

DOI:10.1021/ol102652t

Reference yield:

methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate (1260148-61-5) → C16H13IO4 (1260148-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

1.2: 0 °C

2.1: Me₄N(ICl₂); sodium hydrogencarbonate / dichloromethane / 16 h / 0 °C / Inert atmosphere

3.1: sodium tetrahydroborate / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3.2: 0 °C

With sodium tetrahydroborate; Me₄N(ICl₂); boron tribromide; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ol102652t

Reference yield:

C17H16O5 (1260148-62-6) → C16H13IO4 (1260148-51-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Me₄N(ICl₂); sodium hydrogencarbonate / dichloromethane / 16 h / 0 °C / Inert atmosphere

2.1: sodium tetrahydroborate / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2.2: 0 °C

With sodium tetrahydroborate; Me₄N(ICl₂); sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ol102652t

upstream raw materials:

methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate

C₁₇H₁₆O₅

C₁₇H₁₅IO₅

methyl 2-(3,5-dihydroxyphenyl)acetate

Downstream raw materials:

C₃₀H₄₁IO₆Si

C₃₀H₄₁IO₆Si

C₃₀H₃₉IO₆Si

C₄₀H₄₅IO₆Si