1-(3-AMINO-4-CHLOROBENZENESULFONYL)-1,2,3,4-TETRAHYDROQUINOLINE

Base Information

• Chemical Name: 1-(3-AMINO-4-CHLOROBENZENESULFONYL)-1,2,3,4-TETRAHYDROQUINOLINE
• CAS No.: 847171-51-1
• Molecular Formula: C15H15 Cl N2 O2 S
• Molecular Weight: 322.815
• Mol file: 847171-51-1.mol

Synonyms:Quinoline,1-[(3-amino-4-chlorophenyl)sulfonyl]-1,2,3,4-tetrahydro- (9CI); 2-Chloro-5-[(3,4-dihydro-2H-quinolin-1-yl)sulfonyl]aniline

Chemical Property of 1-(3-AMINO-4-CHLOROBENZENESULFONYL)-1,2,3,4-TETRAHYDROQUINOLINE

Chemical Property:

• Vapor Pressure: 2.12E-10mmHg at 25°C
• Boiling Point: 507°C at 760 mmHg
• Flash Point: 260.4°C
• PSA: 71.78000
• Density: 1.41g/cm³
• LogP: 4.79070
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%min ^*data from raw suppliers

1-(3-Amino-4-chlorobenzenesulfonyl)-1,2,3,4-tetrahydroquinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-AMINO-4-CHLOROBENZENESULFONYL)-1,2,3,4-TETRAHYDROQUINOLINE

There total 2 articles about 1-(3-AMINO-4-CHLOROBENZENESULFONYL)-1,2,3,4-TETRAHYDROQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-((4-chloro-3-nitrophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline (847170-51-8) → 2-Chloro-5-(3,4-dihydro-1(2H)-quinolinylsulfonyl)aniline (847171-51-1)

Guidance literature:

With sodium tetrahydroborate; nickel dibromide; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h;

Reference yield:

→ 2-Chloro-5-(3,4-dihydro-1(2H)-quinolinylsulfonyl)aniline (847171-51-1)

Guidance literature:

upstream raw materials:

1-((4-chloro-3-nitrophenyl)sulfonyl)-1,2,3,4-tetrahydroquinoline

Refernces

• 1、 -. "FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME,AND MEDICINAL USE THEREOF". Page/Page column 15. . Retrieved 2008/12/06.
• 2、 -. "FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF". Page/Page column 128. . Retrieved 2010/11/08.