methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate

Base Information

Chemical Name:methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate
CAS No.:1025370-10-8
Molecular Formula:C₃₉H₄₇N₃O₇
Molecular Weight:669.818
Hs Code.:

Synonyms:methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate

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Chemical Property of methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate

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Technology Process of methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate

There total 1 articles about methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1025368-64-2
(2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoate

: 957475-58-0
methyl (4R)-4-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-L-prolinate hydrochloride

: 1025370-10-8
methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield:

: 1025370-10-8
methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate

: 1025370-13-1
(4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-proline

Guidance literature:: methyl (4R)-[(7-methoxy-2-phenyl-6-vinylquinolin-4-yl)oxy]-1-((2S)-2-{[(pent-4-en-1-yloxy)carbonyl]amino}non-8-enoyl)-L-prolinate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; pH=5;