Technology Process of B 064-055A1
There total 4 articles about B 064-055A1 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-trimethylsilyl-1,4-pentadiyne;
With
ethylmagnesium bromide;
In
tetrahydrofuran;
at 0 ℃;
for 0.333333h;
B 064-051A2;
In
tetrahydrofuran;
at 20 ℃;
With
water; ammonium chloride;
In
tetrahydrofuran;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 1H-imidazole / dichloromethane / 0 - 20 °C
2.1: toluene-4-sulfonic acid / isopropyl alcohol; diethyl ether / 72 h / 20 °C
3.1: Dess-Martin periodane / dichloromethane / 0.5 h / 0 - 20 °C
4.1: ethylmagnesium bromide / tetrahydrofuran / 0.33 h / 0 °C
4.2: 20 °C
With
1H-imidazole; ethylmagnesium bromide; Dess-Martin periodane; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / isopropyl alcohol; diethyl ether / 72 h / 20 °C
2.1: Dess-Martin periodane / dichloromethane / 0.5 h / 0 - 20 °C
3.1: ethylmagnesium bromide / tetrahydrofuran / 0.33 h / 0 °C
3.2: 20 °C
With
ethylmagnesium bromide; Dess-Martin periodane; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; isopropyl alcohol;