6-Chloro-2-hydroxy-3-methylbenzaldehyde

Base Information

Chemical Name:6-Chloro-2-hydroxy-3-methylbenzaldehyde
CAS No.:1310800-53-3
Molecular Formula:C₈H₇ClO₂
Molecular Weight:170.595
Hs Code.:
European Community (EC) Number:872-491-7

Synonyms:6-chloro-2-hydroxy-3-methylbenzaldehyde;1310800-53-3;AKOS014994088;CS-0238781;EN300-200899;Z1267796572

Suppliers and Price of 6-Chloro-2-hydroxy-3-methylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-Chloro-2-hydroxy-3-methylbenzaldehyde

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:170.0134572
Heavy Atom Count:11
Complexity:149

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=C(C=C1)Cl)C=O)O

Technology Process of 6-Chloro-2-hydroxy-3-methylbenzaldehyde

There total 3 articles about 6-Chloro-2-hydroxy-3-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1310800-51-1
(E)-3-chloro-6-methyl-2-(prop-1-enyl)phenol

: 1310800-53-3
6-chloro-2-hydroxy-3-methylbenzaldehyde

Guidance literature:: With sodium periodate; osmium(VIII) oxide; water; In 1,4-dioxane; tert-butyl alcohol; at 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2011.03.030

Reference yield:

: 1310800-49-7
2-(allyloxy)-4-chloro-1-methylbenzene

: 1310800-53-3
6-chloro-2-hydroxy-3-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 210 °C / Neat (no solvent)

2: potassium tert-butylate / dimethyl sulfoxide / 4 h / 55 °C

3: sodium periodate; osmium(VIII) oxide; water / 1,4-dioxane; tert-butyl alcohol / 1 h / 20 °C

With sodium periodate; osmium(VIII) oxide; potassium tert-butylate; water; In 1,4-dioxane; dimethyl sulfoxide; tert-butyl alcohol; 1: Claisen rearrangement;
DOI:10.1016/j.ejmech.2011.03.030

Reference yield:

: 5306-98-9
5-chloro-2-methyl-phenol

: 1310800-53-3
6-chloro-2-hydroxy-3-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / acetonitrile / 3 h / 80 °C

2: 210 °C / Neat (no solvent)

3: potassium tert-butylate / dimethyl sulfoxide / 4 h / 55 °C

4: sodium periodate; osmium(VIII) oxide; water / 1,4-dioxane; tert-butyl alcohol / 1 h / 20 °C

With sodium periodate; osmium(VIII) oxide; potassium tert-butylate; water; potassium carbonate; In 1,4-dioxane; dimethyl sulfoxide; acetonitrile; tert-butyl alcohol; 2: Claisen rearrangement;
DOI:10.1016/j.ejmech.2011.03.030