3,5-Dichloro-4-nitropyridine N-oxide

Base Information

• Chemical Name: 3,5-Dichloro-4-nitropyridine N-oxide
• CAS No.: 18344-58-6
• Molecular Formula: C₅H₂Cl₂N₂O₃
• Molecular Weight: 208.988
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID60441051
• Wikidata: Q82257609
• Mol file: 18344-58-6.mol

Synonyms:18344-58-6;3,5-Dichloro-4-nitropyridine N-oxide;3,5-Dichloro-4-nitropyridine 1-oxide;3,5-dichloro-4-nitro-1-oxidopyridin-1-ium;DTXSID60441051;3,5-Dichloro-4-nitropyridine1-oxide;AKOS015911232;FT-0740749

Chemical Property of 3,5-Dichloro-4-nitropyridine N-oxide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.654
• Boiling Point: 451.206 °C at 760 mmHg
• Flash Point: 226.681 °C
• PSA: 71.28000
• Density: 1.793 g/cm³
• LogP: 2.85330
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 207.9442473
• Heavy Atom Count: 12
• Complexity: 174

Purity/Quality:

99% ^*data from raw suppliers

3,5-DICHLORO-4-NITROPYRIDINE N-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=C(C=[N+]1[O-])Cl)[N+](=O)[O-])Cl

Technology Process of 3,5-Dichloro-4-nitropyridine N-oxide

There total 3 articles about 3,5-Dichloro-4-nitropyridine N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

3,5-dicholoropyridine N-oxide (15177-57-8) → 3,5-dichloro-4-nitropyridine N-oxide (18344-58-6)

Guidance literature:

With sulfuric acid; nitric acid; at 100 ℃; for 5h;

Reference yield:

3,5-dichloropyridine (2457-47-8) → 3,5-dichloro-4-nitropyridine N-oxide (18344-58-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / peracetic acid / CHCl₃; acetic acid / 67 h / 50 °C

2: 71 percent / H₂SO₄, HNO₃ / 5 h / 100 °C

With peracetic acid; sulfuric acid; nitric acid; In chloroform; acetic acid;

Reference yield:

→ 3,5-dichloro-4-nitropyridine N-oxide (18344-58-6)

Guidance literature:

DOI:10.1039/J29670001235

upstream raw materials:

3,5-dicholoropyridine N-oxide

3,5-dichloropyridine

Downstream raw materials:

4-amino-3,5-dichloropyridine-N-oxide