3-(3-Bromo-2-thienyl)-1-propene

Base Information

• Chemical Name: 3-(3-Bromo-2-thienyl)-1-propene
• CAS No.: 33892-67-0
• Molecular Formula: C₇H₇BrS
• Molecular Weight: 203.103
• DSSTox Substance ID: DTXSID80500593
• Wikidata: Q82352314
• Mol file: 33892-67-0.mol

Synonyms:3-(3-BROMO-2-THIENYL)-1-PROPENE;33892-67-0;3-bromo-2-prop-2-enylthiophene;3-Bromo-2-(prop-2-en-1-yl)thiophene;MFCD07775155;2-Allyl-3-bromothiophene;SCHEMBL1205997;DTXSID80500593;AKOS016017191

Chemical Property of 3-(3-Bromo-2-thienyl)-1-propene

Chemical Property:

• Vapor Pressure: 0.205mmHg at 25°C
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 201.94518
• Heavy Atom Count: 9
• Complexity: 103

Purity/Quality:

97% ^*data from raw suppliers

3-(3-Bromo-2-thienyl)-1-propene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CCC1=C(C=CS1)Br

Technology Process of 3-(3-Bromo-2-thienyl)-1-propene

There total 3 articles about 3-(3-Bromo-2-thienyl)-1-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(3-bromo-2-thienyl)lithium (19162-82-4) + allyl bromide (106-95-6) → 2-allyl-3-bromothiophene (33892-67-0)

Guidance literature:

In diethyl ether; for 10h; Ambient temperature;

DOI:10.1021/jo00352a011

Reference yield: 59.0%

3-Bromothiophene (872-31-1) + allyl bromide (106-95-6) → 2-allyl-3-bromothiophene (33892-67-0)

Guidance literature:

3-Bromothiophene; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at 0 ℃; for 1h; Inert atmosphere; Schlenk technique;

allyl bromide; In tetrahydrofuran; hexane; at 0 - 25 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.202001523

Reference yield:

→ 2-allyl-3-bromothiophene (33892-67-0)

Guidance literature:

Aus 2,3-Dibromthiophen (9b), BuLi u. Allylbromid;

upstream raw materials:

(3-bromo-2-thienyl)lithium

allyl bromide

3-Bromothiophene

Downstream raw materials:

2-allyl-3-methylthiophene

(S)-N-(3-(3-bromothiophen-2-yl)propylidene)-2,4,6-trimethylbenzenesulfinamide