Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

Base Information

Chemical Name:Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester
CAS No.:111543-47-6
Molecular Formula:C₃₀H₅₁ClN₃O₉P
Molecular Weight:664.176
Hs Code.:

Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

Synonyms:Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

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Chemical Property of Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

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Technology Process of Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

There total 4 articles about Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 99592-73-1
(Carbamoyl-{(3aR,4R,6R,6aR)-6-[(4-chloro-phenoxy)-hexadecyloxy-phosphoryloxymethyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylcarbamoyl}-methyl)-carbamic acid tert-butyl ester

: 111543-47-6
Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

Guidance literature:: With trifluoroacetic acid; In water;
DOI:10.1248/cpb.35.3523

Reference yield:

: 99592-66-2
2-Amino-N-(2,3-O-isopropylidene-β-D-ribofuranosyl)malonamide

: 111543-47-6
Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / dimethylformamide

2: 2.) N,N-dimethylaminopyridine / 1.) dioxane

3: 84 percent / trifluoroacetic acid / H₂O

With dmap; trifluoroacetic acid; In water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.35.3523

Reference yield:

: 99592-67-3
2-(tert-Butoxycarbonylamino)-N-(2,3-O-isopropylidene-β-D-ribofuranosyl)malonamide

: 111543-47-6
Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-2-carbamoyl-acetylamino)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester 4-chloro-phenyl ester hexadecyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) N,N-dimethylaminopyridine / 1.) dioxane

2: 84 percent / trifluoroacetic acid / H₂O

With dmap; trifluoroacetic acid; In water;
DOI:10.1248/cpb.35.3523