C₃₉H₆₈O

Base Information

• Chemical Name: C₃₉H₆₈O
• CAS No.: 887278-85-5
• Molecular Formula: C₃₉H₆₈O
• Molecular Weight: 552.968
• Mol file: 887278-85-5.mol

Synonyms:C₃₉H₆₈O

Chemical Property of C₃₉H₆₈O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₆₈O

There total 8 articles about C₃₉H₆₈O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

5-(6-benzyloxy-(3R)-3-methylhexylsulfonyl)-1-tert-butyl-1H-tetrazole (887278-74-2) + C25H48O (887278-84-4) → C39H68O (887278-85-5)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/jo4005298

Reference yield:

4-benzyloxybutanal (5470-84-8) → C39H68O (887278-85-5)

Guidance literature:

Multi-step reaction with 6 steps

1.1: chloroform / 3 h / Reflux

1.2: 20 °C

2.1: copper(I) bromide dimethylsulfide complex; (R)-(-)-1-[(S)-2-(diphenylphosphino)ferrocene]ethyldicyclohexylphosphine / tert-butyl methyl ether / -78 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / -78 °C

4.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 0 - 20 °C

5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C

6.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C

With lithium aluminium tetrahydride; copper(I) bromide dimethylsulfide complex; (R)-(-)-1-[(S)-2-(diphenylphosphino)ferrocene]ethyldicyclohexylphosphine; di-isopropyl azodicarboxylate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; tert-butyl methyl ether; chloroform;

DOI:10.1021/jo4005298

Reference yield:

C41H68OSi (887278-82-2) → C39H68O (887278-85-5)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C

2: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / 2 h / 20 °C / Molecular sieve

3: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C

With tetrapropylammonium perruthennate; tetrabutyl ammonium fluoride; 4-methylmorpholine N-oxide; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo4005298

upstream raw materials:

C₄₁H₆₈OSi

4-benzyloxybutanal

(+)-(R)-3-methyl-6-benzyloxy-thiohexanoic acid (S)-ethyl ester

5-(6-benzyloxy-(3R)-3-methylhexylsulfonyl)-1-tert-butyl-1H-tetrazole