Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro-

Base Information

• Chemical Name: Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro-
• CAS No.: 16611-68-0
• Molecular Formula: C₁₂H₈ClO₂P
• Molecular Weight: 250.621
• European Community (EC) Number: 929-115-2
• DSSTox Substance ID: DTXSID20884920
• Nikkaji Number: J591.296B
• Wikipedia: 2,2%27-Biphenylene_phosphorochloridite
• Wikidata: Q81007702
• Mol file: 16611-68-0.mol

Synonyms:Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro-;16611-68-0;Dibenzo(d,f)(1,3,2)dioxaphosphepin, 6-chloro-;2,2'-Biphenylylenephosphorous acid chloride;SCHEMBL339291;DTXSID20884920;2,2'-Biphenylylene phosphorochloridite;Chloro(biphenyl-2,2'-diylbisoxy)phosphine;6-chlorodibenzo[d,f][1,3,2]dioxaphosphepin;1,1'-biphenyl-2,2'-diyl phosphorochloridite;2,2'-Biphenyldiol, cyclic phosphorochloridite;6-Chlorodibenzo[d,f][1,3,2]dioxaphosphepine;6-Chlorodibenzo[d,f][1,3,2]dioxaphosphepine #;Phosphorochloridous acid, cyclic 2,2'-biphenylylene ester

Chemical Property of Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro-

Chemical Property:

• Vapor Pressure: 0.000213mmHg at 25°C
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 249.9950442
• Heavy Atom Count: 16
• Complexity: 227

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3OP(O2)Cl

Technology Process of Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro-

There total 4 articles about Dibenzo[d,f][1,3,2]dioxaphosphepin, 6-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2'-dihydroxybiphenyl (1806-29-7) → 6-chloro-dibenzo[d,f][1,3,2]-dioxaphosphepin (16611-68-0)

Guidance literature:

With phosphorus trichloride; for 2h; Inert atmosphere; Reflux;

DOI:10.1016/j.jorganchem.2010.08.026

Reference yield: 99.0%

2,2'-Bis(trimethylsiloxy)biphenyl (1094-10-6) → 6-chloro-dibenzo[d,f][1,3,2]-dioxaphosphepin (16611-68-0)

Guidance literature:

With phosphorus trichloride; In acetonitrile; for 3h; Inert atmosphere;

DOI:10.1039/c9dt00893d

Reference yield: 94.0%

→ 6-chloro-dibenzo[d,f][1,3,2]-dioxaphosphepin (16611-68-0)

Guidance literature:

With phosphorus trichloride; In 1-methyl-pyrrolidin-2-one; at 92 ℃; for 2h; Inert atmosphere;

upstream raw materials:

2,2'-dihydroxybiphenyl

phosphorus trichloride

2,2'-Bis(trimethylsiloxy)biphenyl

Downstream raw materials:

2'-Dibenzo[d,f][1,3,2]dioxaphosphepin-6-yloxy-biphenyl-2-ol

(5,7-dioxa-6-phospha-dibenzo[a,c]cyclohepten-6-yl)-[2-(5-phenyl-imidazol-1-yl)-cyclohexyl]-amine

2,2'-biphenylyl 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate

6,6′-[(3,3′-di-tert-butyl-5,5′-dimethoxy-1,1′-biphenyl-2,2′-diyl)bis(oxy)]bis(di-benzo[d,f][1,3,2]dioxaphosphepin)