[6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

Base Information

Chemical Name:[6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester
CAS No.:858916-49-1
Molecular Formula:C₂₅H₃₅O₅PSi
Molecular Weight:474.609
Hs Code.:

Synonyms:[6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

Suppliers and Price of [6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of [6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

There total 6 articles about [6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [6-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-4-methyl-hex-4-enyl]-phosphonic acid dimethyl ester

: 858916-49-1
[6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/ol051040g

Reference yield:

: 858918-41-9
1-[(2Z)-3-methyl-5-(1,1,2,2-tetramethyl-1-silapropoxy)pent-2-enyloxy]-2,2-dimethyl-1,1-diphenyl-1-silapropane

: 858916-49-1
[6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 93 percent / CSA / methanol / 0.5 h / 0 °C

2.1: CrO₃; pyridine / CH₂Cl₂ / 0.5 h / 20 °C

3.1: n-BuLi / toluene / 0.5 h / -78 °C

3.2: toluene / 0.5 h / -78 °C

4.1: 1.23 g / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

With pyridine; chromium(VI) oxide; n-butyllithium; camphor-10-sulfonic acid; Dess-Martin periodane; In methanol; dichloromethane; toluene;
DOI:10.1021/ol051040g

Reference yield:

: 86462-83-1
(Z)-5-(tert-butyldimethylsilyloxy)-3-methylpent-2-en-1-ol

: 858916-49-1
[6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-2-oxo-hex-4-enyl]-phosphonic acid dimethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: 3.38 g / imidazole / CH₂Cl₂ / 0.5 h / 20 °C

2.1: 93 percent / CSA / methanol / 0.5 h / 0 °C

3.1: CrO₃; pyridine / CH₂Cl₂ / 0.5 h / 20 °C

4.1: n-BuLi / toluene / 0.5 h / -78 °C

4.2: toluene / 0.5 h / -78 °C

5.1: 1.23 g / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

With pyridine; 1H-imidazole; chromium(VI) oxide; n-butyllithium; camphor-10-sulfonic acid; Dess-Martin periodane; In methanol; dichloromethane; toluene;
DOI:10.1021/ol051040g