2-Chloro-3-methoxypropionic Acid

Base Information

• Chemical Name: 2-Chloro-3-methoxypropionic Acid
• CAS No.: 2544-05-0
• Molecular Formula: C4H7ClO3
• Molecular Weight: 138.551
• Hs Code.: 2918990090
• European Community (EC) Number: 638-903-2
• DSSTox Substance ID: DTXSID70558220
• Nikkaji Number: J2.294.673K
• Mol file: 2544-05-0.mol

Synonyms:2-Chloro-3-methoxypropionic Acid;2544-05-0;2-Chloro-3-methoxypropanoic acid;MFCD03093624;2-CHLORO-3-METHOXYPROPIONICACID;Propanoic acid, 2-chloro-3-methoxy-;SCHEMBL838514;DTXSID70558220;SSWGTERYCJZJPQ-UHFFFAOYSA-N;AMY11466;CAA54405;Propanoic acid,2-chloro-3-methoxy-;AKOS006223973;AC-2410;BS-43988;SY051207;A5129;C1688;T70661

Chemical Property of 2-Chloro-3-methoxypropionic Acid

Chemical Property:

• Vapor Pressure: 0.0204mmHg at 25°C
• Refractive Index: 1.447
• Boiling Point: 232.7 °C at 760 mmHg
• PKA: 2.42±0.10(Predicted)
• Flash Point: 94.5 °C
• PSA: 46.53000
• Density: 1.291 g/cm³
• LogP: 0.32480
• Storage Temp.: 2-8°C
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 138.0083718
• Heavy Atom Count: 8
• Complexity: 83.4

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-3-methoxypropionic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC(C(=O)O)Cl

Technology Process of 2-Chloro-3-methoxypropionic Acid

There total 5 articles about 2-Chloro-3-methoxypropionic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-dichloro-3-methoxy-propene (60988-81-0) → 2-chloro-3-methoxy propanoic acid (2544-05-0)

Guidance literature:

With formic acid; chlorine; anschliessendes Erhitzen mit Wasser;

Reference yield:

2-chloro-3-methoxypropanenitrile (31413-66-8) → 2-chloro-3-methoxy propanoic acid (2544-05-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

2-chloro-1-methoxy-3-nitro-propane (89125-55-3) → 2-chloro-3-methoxy propanoic acid (2544-05-0)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

1,1-dichloro-3-methoxy-propene

2-chloro-3-methoxypropanenitrile

2-chloro-3-methoxy-propan-1-ol

2-chloro-1-methoxy-3-nitro-propane

Downstream raw materials:

3-methoxy-2-aminopropionic acid

N-benzyl-2-chloro-3-methoxy-propionamide