Antazoline phosphate

Base Information

• Chemical Name: Antazoline phosphate
• CAS No.: 154-68-7
• Molecular Formula: C₁₇H₁₉N₃*H₃O₄P
• Molecular Weight: 363.353
• Hs Code.: 2933290000
• European Community (EC) Number: 205-831-4
• NSC Number: 755865
• UNII: VPR5FPH326
• DSSTox Substance ID: DTXSID00165507
• Wikidata: Q27291961
• NCI Thesaurus Code: C47399
• ChEMBL ID: CHEMBL1200550
• Mol file: 154-68-7.mol

Synonyms:Antazoline Hydrochloride

Chemical Property of Antazoline phosphate

Chemical Property:

• Appearance/Colour: COA
• Vapor Pressure: 3.31E-09mmHg at 25°C
• Melting Point: 194-198°
• Boiling Point: 475.5 °C at 760 mmHg
• Flash Point: 241.4 °C
• PSA: 115.20000
• Density: 0.975?g/mL?at 25?°C(lit.)
• LogP: 1.53070
• Storage Temp.: Refrigerator
• Solubility.: DMSO, Methanol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 363.13479319
• Heavy Atom Count: 25
• Complexity: 364

Purity/Quality:

99%, ^*data from raw suppliers

Antazoline phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN=C(N1)CN(CC2=CC=CC=C2)C3=CC=CC=C3.OP(=O)(O)O
• Uses: Antazoline Phosphate acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical.

Technology Process of Antazoline phosphate

There total 1 articles about Antazoline phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ antazoline phosphate (154-68-7)

Guidance literature:

Reference yield:

antazoline phosphate (154-68-7) → antazoline hydrogen oxalate

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water

2: 22 °C

With sodium hydroxide; In water;

DOI:10.1080/15421406.2014.905041

Reference yield:

antazoline phosphate (154-68-7) → antazoline fumarate

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water

2: 22 °C

With sodium hydroxide; In water;

DOI:10.1080/15421406.2014.905041

Refernces

• 1、 -. "Polystyrene sulfonate containing opthalmic solutions". . . Retrieved 2008/06/13.