(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Base Information

Chemical Name:(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol
CAS No.:1263166-90-0
Molecular Formula:C₁₀H₁₄O
Molecular Weight:150.221
Hs Code.:

Synonyms:(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Suppliers and Price of (1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol >90.0%(GC)
100mg
$ 349.00

SynChem
Exo-Bicyclo[6.1.0]non-4-yn-9-yl-methanol 95%
100 mg
$ 250.00

SynChem
Bicyclo[6.1.0]non-4-yn-9-yl-methanol (Endo:Exo=1:2-3) 95%
100 mg
$ 215.00

SynChem
(1R,8S,9S)-BICYCLO[6.1.0]NON-4-YN-9-YLMETHANOL (ENDO 80%) 80%
100 mg
$ 215.00

SynChem
(1R,8S,9S)-BICYCLO[6.1.0]NON-4-YN-9-YLMETHANOL (ENDO 95%) 95%
100 mg
$ 495.00

Sigma-Aldrich
(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol for Copper-free Click Chemistry
100mg
$ 298.00

Ambeed
(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol 90%
1g
$ 393.00

Ambeed
(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol 90%
250mg
$ 146.00

Ambeed
(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol 90%
100mg
$ 79.00

Ambeed
(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol 90%
50mg
$ 54.00

Total 20 raw suppliers

Chemical Property of (1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Chemical Property:

Melting Point:64 °C
Boiling Point:256.5±9.0 °C(Predicted)
Density:1.08±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol >90.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Alcohol functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide functionalized compounds or biomolecules without the need for a copper catalyst to result in a stable triazole linkage.

Technology Process of (1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

There total 12 articles about (1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: C₁₆H₁₄Co₂O₇

: 1263166-90-0
(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Guidance literature:: With trimethylamine-N-oxide; In dichloromethane; for 4h;
DOI:10.1039/c5cc01522g

Reference yield: 68.0%

: 1263291-39-9
C₁₂H₁₈O₂

: 1263166-90-0
(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Guidance literature:: C₁₂H₁₈O₂; With diisobutylaluminium hydride; In diethyl ether; at 0 - 20 ℃;

With bromine; In dichloromethane; at 20 ℃; for 0.0833333h;

With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 1.5h; Reflux;
DOI:10.1002/anie.201915079

Reference yield: 55.0%

: ((1R,8S,9S)-4,5-dibromobicyclo[6.1.0]nonan-9-yl)methanol

: 1263166-90-0
(1R,8S,9S)‐bicyclo[6.1.0]non‐4‐yn‐9‐ylmethanol

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 3h; Reflux; Inert atmosphere;
DOI:10.1002/chem.201702104