[6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester

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Chemical Name:[6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester
CAS No.:262426-62-0
Molecular Formula:C₂₅H₂₆ClNO₃
Molecular Weight:423.939
Hs Code.:

Synonyms:[6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester

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Chemical Property of [6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester

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Technology Process of [6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester

There total 1 articles about [6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 197963-34-1
ethyl 2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-2-oxoacetate

: 262426-62-0
[6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester

Guidance literature:: ethyl 2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-2-oxoacetate; With sodium tetrahydroborate; In tetrahydrofuran; water; at 20 ℃; for 1h;

With ammonia; In tetrahydrofuran; water; at 20 ℃; for 1h;

Reference yield: 68.0%

: 262426-62-0
[6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester

: [6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid

Guidance literature:: [6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizin-5-yl]hydroxyacetic acid ethyl ester; With potassium hydroxide; In ethanol; water; at 20 ℃; for 16h;

With hydrogenchloride; In H₂₀; pH=3;