2-(Tributylstannyl)thiazole

Base Information

• Chemical Name: 2-(Tributylstannyl)thiazole
• CAS No.: 121359-48-6
• Molecular Formula: C15H29NSSn
• Molecular Weight: 374.178
• Hs Code.: 2934100090
• European Community (EC) Number: 626-624-9
• DSSTox Substance ID: DTXSID10376849
• Mol file: 121359-48-6.mol

Synonyms:2-(Tributylstannyl)thiazole;121359-48-6;2-Tributylstannylthiazole;2-(Tributylstannyl)-1,3-thiazole;tributyl(1,3-thiazol-2-yl)stannane;Tributyl-2-thiazolylstannane;Thiazole,2-(tributylstannyl)-;tributylstannylthiazole;MFCD01319057;THIAZOLE, 2-(TRIBUTYLSTANNYL)-;tributyl-2-thiazolyltin;2-(Tributyltin)thiazole;(2-thiazolyl)tributyltin;2-tributylstannyl-thiazol;thiazol-2-yl tributyltin;tributyl(2-thiazolyl)tin;2-tributylstannyl thiazole;2-tributylstannyl-thiazole;2-tributylstannanylthiazole;2-tributylstannanyl thiazole;2-Tributylstannyl(thiazole);2-tri-n-butylstannylthiazole;SCHEMBL42407;tri-n-butyl(2-thiazolyl)tin;2-(tributylstannanyl)thiazole;2-(tributylstannyl) thiazole;tri-n-butyl-thiazol-2-yl tin;(Thiazol-2-yl)tributylstannane;tributyl(thiazol-2-yl)stannane;2-(tri n-butylstannyl)thiazole;2-Tributylstannylthiazole, 97%;DTXSID10376849;tri-n-butyl-(thiazol-2-yl)-tin;WUOFQGMXQCSPPV-UHFFFAOYSA-N;2-TRIBUTYLSTANNANYL-THIAZOLE;AMY18364;2-(tributylstannanyl)-1,3-thiazole;AKOS015843269;2-(TRI-N-BUTYLSTANNYL)THIAZOLE;AB08881;PS-9716;SY011817;CS-0040965;FT-0676565;EN300-222510;J-506651

Chemical Property of 2-(Tributylstannyl)thiazole

Chemical Property:

• Vapor Pressure: 4.23E-05mmHg at 25°C
• Melting Point: 307-309 °C(lit.)
• Refractive Index: n20/D 1.5200(lit.)
• Boiling Point: 361.7 °C at 760 mmHg
• PKA: 2.73±0.10(Predicted)
• Flash Point: 172.6 °C
• PSA: 41.13000
• Density: 1.1900 g/mL at 25 °C(lit.)
• LogP: 5.19920
• Storage Temp.: Keep Cold
• Solubility.: Not miscible or difficult to mix.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 10
• Exact Mass: 375.104274
• Heavy Atom Count: 18
• Complexity: 189

Purity/Quality:

97% ^*data from raw suppliers

2-(Tributylstannyl)-1,3-thiazole 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T; N; Xi
• Hazard Codes: T,N,Xi
• Statements: 21-25-36/38-48/23/25-50/53
• Safety Statements: 35-36/37/39-45-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC[Sn](CCCC)(CCCC)C1=NC=CS1
• Uses: Reagent for arylation of thiazole by Stille cross-coupling.1 Used as reagent for arylation of thiazole by Stille cross-coupling. Reagent for arylation of thiazole by Stille cross-coupling.

Technology Process of 2-(Tributylstannyl)thiazole

There total 4 articles about 2-(Tributylstannyl)thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-bromo-1,3-thiazole (3034-53-5,215777-74-5) + tributyltin chloride (1461-22-9) → 2-(tri-n-butylstannyl)thiazole (121359-48-6)

Guidance literature:

2-bromo-1,3-thiazole; With n-butyllithium; In hexane; at -78 ℃; for 1h; Inert atmosphere;

tributyltin chloride; In hexane; Inert atmosphere;

Reference yield: 100.0%

tributyltin chloride (1461-22-9) + 2-(trimethylsilyl)thiazole (79265-30-8) → 2-(tri-n-butylstannyl)thiazole (121359-48-6)

Guidance literature:

2-(trimethylsilyl)thiazole; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.333333h; Inert atmosphere;

tributyltin chloride; In diethyl ether; hexane; at -78 - 20 ℃;

Reference yield: 90.0%

→ 2-(tri-n-butylstannyl)thiazole (121359-48-6)

Guidance literature:

upstream raw materials:

tributyltin chloride

2-bromo-1,3-thiazole

2-(trimethylsilyl)thiazole

Downstream raw materials:

C₂₄H₂₂N₂OS

C₂₇H₂₆N₂OS

C₂₄H₂₅NO

C₂₄H₂₅NO