Technology Process of N-(2-cyclohexylideneethyl)-4-methyl-N-(4-oxobutyl)benzenesulfonamide
There total 10 articles about N-(2-cyclohexylideneethyl)-4-methyl-N-(4-oxobutyl)benzenesulfonamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / chloroform / 3 h
2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h
2.2: 18 h
3.1: trifluoroacetic acid / chloroform; water / 3 h
With
sodium hydride; triethylamine; trifluoroacetic acid;
In
chloroform; water; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ja4047312
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diisobutylaluminium hydride / toluene / 3 h / -78 - 20 °C
2.1: N-chloro-succinimide; dimethylsulfide / dichloromethane / 3 h / -40 - 20 °C
3.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h
3.2: 18 h
4.1: trifluoroacetic acid / chloroform; water / 3 h
With
N-chloro-succinimide; dimethylsulfide; sodium hydride; diisobutylaluminium hydride; trifluoroacetic acid;
In
dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/ja4047312
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / mineral oil; tetrahydrofuran / 1 h
1.2: 18 h
2.1: diisobutylaluminium hydride / toluene / 3 h / -78 - 20 °C
3.1: N-chloro-succinimide; dimethylsulfide / dichloromethane / 3 h / -40 - 20 °C
4.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h
4.2: 18 h
5.1: trifluoroacetic acid / chloroform; water / 3 h
With
N-chloro-succinimide; dimethylsulfide; sodium hydride; diisobutylaluminium hydride; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/ja4047312
