C₂₆H₄₀N₂O₉Si

Base Information

• Chemical Name: C₂₆H₄₀N₂O₉Si
• CAS No.: 1456708-22-7
• Molecular Formula: C₂₆H₄₀N₂O₉Si
• Molecular Weight: 552.697
• Mol file: 1456708-22-7.mol

Synonyms:C₂₆H₄₀N₂O₉Si

Chemical Property of C₂₆H₄₀N₂O₉Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₄₀N₂O₉Si

There total 3 articles about C₂₆H₄₀N₂O₉Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(S)-2-(trimethylsilyl)ethyl 2-((R)-2-(((2R,4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanamido)propanoate (387881-21-2) → C26H40N2O9Si (1456708-22-7)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; ethyl acetate; at 20 ℃; for 12h;

DOI:10.1002/chem.201301074

Reference yield:

benzyl 2-acetamido-4,6-O-benzylidene-3-O-[(R)-1-carboxyethyl]-2-deoxy-α-D-glucopyranoside (73089-68-6) → C26H40N2O9Si (1456708-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / tetrahydrofuran; dichloromethane / 5 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate / 12 h / 20 °C

With palladium 10% on activated carbon; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;

DOI:10.1002/chem.201301074

Reference yield:

(S)-Alanin-(2-trimethylsilylethyl)ester (103225-23-6) → C26H40N2O9Si (1456708-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / tetrahydrofuran; dichloromethane / 5 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate / 12 h / 20 °C

With palladium 10% on activated carbon; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;

DOI:10.1002/chem.201301074

upstream raw materials:

benzyl 2-acetamido-4,6-O-benzylidene-3-O-[(R)-1-carboxyethyl]-2-deoxy-α-D-glucopyranoside

(S)-2-(trimethylsilyl)ethyl 2-((R)-2-(((2R,4aR,6S,7R,8R,8aS)-7-acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanamido)propanoate

(S)-Alanin-(2-trimethylsilylethyl)ester

Downstream raw materials:

C₃₅H₄₁N₂O₁₂P

C₄₀H₅₃N₂O₁₂PSi