5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER

Base Information

Chemical Name:5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER
CAS No.:78606-80-1
Molecular Formula:C₈H₁₆O₅
Molecular Weight:192.212
Hs Code.:
Mol file:78606-80-1.mol

Synonyms:5(S), 6(R), 7-trihydroxyheptanoic acid methyl ester

Suppliers and Price of 5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5(S),6(R)-7-trihydroxymethylHeptanoate
2.5mg
$ 110.00

TRC
5(S),6(R)-7-trihydroxymethylHeptanoate
1mg
$ 55.00

Tocris
BML111
10
$ 182.00

Sigma-Aldrich
5(S),6(R),7-Trihydroxyheptanoic acid methyl ester ≥98% (HPLC)
25mg
$ 528.00

Sigma-Aldrich
5(S),6(R),7-Trihydroxyheptanoic acid methyl ester ≥98% (HPLC)
5mg
$ 122.00

Cayman Chemical
5(S),6(R)-7-trihydroxymethyl Heptanoate ≥95%
5mg
$ 221.00

Cayman Chemical
5(S),6(R)-7-trihydroxymethyl Heptanoate ≥95%
10mg
$ 389.00

Cayman Chemical
5(S),6(R)-7-trihydroxymethyl Heptanoate ≥95%
1mg
$ 50.00

Biorbyt Ltd
bML-111 >98%
25 mg
$ 389.30

Biorbyt Ltd
bML-111 >98%
5 mg
$ 154.70

Total 19 raw suppliers

Chemical Property of 5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER

Chemical Property:

Boiling Point:360.8±42.0 °C(Predicted)
PKA:13.74±0.20(Predicted)
Density:1?+-.0.06 g/cm3(Predicted)
Storage Temp.:?20°C
Solubility.:H2O: ≥20mg/mL

Purity/Quality:

97% ^*data from raw suppliers

5(S),6(R)-7-trihydroxymethylHeptanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description BML-111 (78606-80-1) novel truncated analog of lipoxin A4 which retains anti-inflammatory activity.1 Inhibits LTB4-induced leukocyte chemotaxis, IC50=5 nM).1 Attenuates hemorrhagic shock-induced acute lung injury in a rat model.2 Displays hepatoprotective effects in acetaminophen-induced liver injury in mice.3 Limits inflammatory damage in the cerebral cortex and helps maintain blood brain barrier integrity in a rat model of ischemic stroke.4 Attenuates renal ischemia/reperfusion injury via activation of p38 MAPK/PPARa/HO-1 pathway.5
Uses 5(S),6(R)-7-trihydroxymethyl Heptanoate is a potent lipoxin A4 agonist.

Technology Process of 5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER

There total 7 articles about 5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 78606-78-7
methyl (E,5S,6R)-5,6,7-trihydroxyhept-2-enoate

: 78606-80-1
5(S), 6(R), 7-trihydroxyheptanoic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 25 ℃; under 760 Torr;
DOI:10.1016/S0040-4039(01)90241-2

Reference yield:

: 910658-46-7
(E)-(5S,6R)-5,6,7-Trihydroxy-hept-2-enoic acid methyl ester

: 78606-80-1
5(S), 6(R), 7-trihydroxyheptanoic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; at 20 ℃;
DOI:10.1016/S0040-4020(02)00045-5

Reference yield:

: 452-51-7,13046-70-3,29780-54-9,36792-87-7,36792-88-8,113890-35-0,113890-38-3
5-(hydroxymethyl)oxolane-2,4-diol

: 21204-67-1,2605-67-6
methyl (triphenylphosphoranylidene)acetate

: 78606-80-1
5(S), 6(R), 7-trihydroxyheptanoic acid methyl ester

Guidance literature:: 5-(hydroxymethyl)oxolane-2,4-diol; methyl (triphenylphosphoranylidene)acetate; In tetrahydrofuran; at 75 ℃;

With hydrogen; palladium on activated charcoal; In ethanol; at 25 ℃;